James DuBois is the Hubert Mäder Professor of Health Care Ethics and Director of the Bander Center for Medical Business Ethics and the Social Science Research Group at Saint Louis University. He is also an Adjunct Professor of Medicine at the Washington University School of Medicine, where he directs the Center for Clinical Research Ethics within their NIH-funded Institute for Clinical and Translational Science. He is the founding Editor (with Ana Iltis) of Narrative Inquiry in Bioethics: A Journal of Qualitative Research, published by Johns Hopkins University Press. He completed his PhD in philosophy at the International Academy of Philosophy in Liechtenstein and his DSc in psychology at the University of Vienna. He regularly teaches "Interdisciplinary Research Methods in Health Care Ethics," "Directed Empirical Research in Bioethics," and "Psychosocial Foundations of Ethics" within the PhD Program in Health Care Ethics. He has received a Faculty Excellence Award from the Student Government Association at Saint Louis University. In 2010, he received the Society of Research Administrator's International Rose Award for best publication.
His research interests include research ethics in mental health, preventing wrongdoing in healthcare, ethics in organ transplantation, moral development and education, and empirical research on ethical issues.
He has served on numerous national committees on organ transplantation, including: the Institute of Medicine's committee on increasing rates of organ donation; the Canadian Council for Donation and Transplantation's Forum on Donation after Cardiac Death; the United Network for Organ Sharing's Regional Review Board for Livers; and Mid-America Transplant Services' committee for non-heart-beating organ donation. In the area of research ethics, he serves on a National Institute of Drug Abuse Data Safety Monitoring Board and is a member of the NIH study section on Social and Ethical Issues in Research. He is also a member of the Institutional Review Board and Ethics Committee at St. Anthony's Medical Center in St. Louis.
"Restoring Professionalism and Integrity in Research (RePAIR)," $500,000 funded by NIH (Administrative Supplement to WU ICTS). September 17, 2007-May 31, 2012.
DuBois is serving as Project Director for this project and PI of the SLU subaward ($476,564). The project involves developing a curriculum for a remediation training program for investigators caught violating the rules for the responsible conduct of research.
"ORI Research Integrity Casebook," $155,579 funded by the Office of Research Integrity . March 1, 2011-September 30, 2012.
The major goal of this project is to produce a casebook that is suitable for use in face-to-face training in the responsible conduct of research.
"Environmental Factors Predictive of Misbehavior in Collaborative Health Research," National Institutes of Health (1R21RR026313-01). 9/25/2009-8/31/2010. $376,000. Principal Investigator.
"Environmental Factors Associated with Professional Misconduct in Medical Research and Practice," BF Foundation. 1/1/2009-12/31/2011. $100,000. Principal Investigator.
"Responsible Conduct of Research Instructional Assessment Program. Part II," Office of Research Integrity, Contract, 7/1/2008-9/30/2009. $60,000, Principal Investigator.
"Center for Clinical Research Ethics," within the Washington University of St. Louis, Institute for Clinical and Translational Science. (NIH: 1 U54 RR023496-01A1, Principal Investigator: Polonsky, K.) 9/1/2007-8/31/2012. Role: 15% effort as Director. $500,000 subcontract with St. Louis University, DuBois, Principal Investigator.
"Best Practices in Mental Health Research Ethics Conference Series," National Institute of Mental Health (1R13MH079690). 9/1/2007 – 8/31/2011. $200,000. Principal Investigator.
"Lay and Professional Attitudes Toward Uncontrolled Donation after Circulatory Determination of Death: A Pilot Study", Greenwall Foundation, $52,000. 7/1/2007-6/30/2008. Principal Investigator.
"Responsible Conduct of Research Instructional Assessment Project," Office of Research Integrity, Responsible Conduct of Research Resource Development Program, 06/01/06 - 10/31/07, $50,000. Principal Investigator.
"Behavioral Health Research: An Ethics Case Compendium and Instructional Method," Office of Research Integrity, Responsible Conduct of Research Resource Development Program, 9/01/03 - 8/31/04, $25,000 direct costs. Principal Investigator. See www.emhr.net for emerging products.
"Ethical Issues in Behavioral Health Research," National Institute of Health, 1 T15 HL072453-01, 9/27/02 – 9/26/05, $527,961 direct costs. Principal Investigator. See www.emhr.net for information on the training program.
"Lay Attitudes Toward Death Criteria and Organ Procurement. A Structured Interview Study." 10/1/2000 – 9/30/2001. $15,000 from Quest for the Gift of Life Foundation for joint project with Intermountain Donor Services. Principal Investigator.
Viktor Frankl Institute of Logotherapy, Abilene, TX. $9,200 grant to produce translation of Viktor Frankl's Theorie und Therapie der Neurosen, (Munich: Reinhardt, 1993, original 1967).
Beaumont Faculty Development Fund. Submitted March 1998. $5,000. Study entitled: "Prolonging and Shortening Life: An International Study on the Moral Reasoning of Medical Personnel". Principal Investigator.
DuBois, J.M., Kraus, E., Vasher, M., " The Development of a Taxonomy of Wrongdoing in Medical Practice and Research," American Journal of Preventive Medicine. (in press).
DuBois, J.M., et al., "Environmental Factors Contributing to Wrongdoing in Medicine: A Criterion-Based Review of Studies and Cases," Ethics & Behavior. (in press).
DuBois, J.M., et al., "Ethical Issues in Mental Health Research: The Case for Community Engagement," Current Opinions in Psychiatry, 24 (2011): 208-214.
DuBois, J.M., "The Ethics of Creating and Responding to Doubts about Death Criteria," Journal of Medicine and Philosophy, 35 (2010): 365-380.
DuBois, J.M., Schilling, D., Heitman, E., Steneck, N., Kon, A., "Instruction in the Responsible Conduct of Research: An Inventory of Programs and Materials within CTSAs," Clinical and Translational Science, 3, 3 (2010): 109-111.
DuBois, J.M., Dueker, J.M., "Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report," Journal of Research Administration, XL, 1, (2009): 49-70.
DuBois, J.M., Cottler, L., Callahan, C., "The Attitudes of Females in Drug Court Toward Additional Safeguards in HIV Prevention Research," Prevention Science: In press (pp. 1-8 in Springer’s Online First content).
DuBois, J.M., Waterman, A., Iltis, A., Anderson, J., "Is Rapid Organ Recovery a Good Idea? An Exploratory Study of the Public’s Knowledge and Attitudes," American Journal of Transplantation, 9, (2009): 2392-2399.
"What Counts as Empirical Research in Bioethics and Where Do We Find the Stuff?" American Journal of Bioethics, 9,6-7 (2009): 70-72.
"The Biomedical Ethics Ontology Proposal: Excellent Aims, Questionable Methods," Journal of Empirical Research on Human Research Ethics, 4, 1, (2009): 59-62.
"Increasing Rates of Organ Donation: Engaging the Institute of Medicine’s Boldest Recommendation," Journal of Clinical Ethics, 20, 1 (2009): 13-22.
"Response to Commentaries on 'Increasing Rates of Organ Donation'," Journal of Clinical Ethics, 20, 1 (2009): 41-43.
DuBois, J.M. & Volpe, R.L. "Organ donation and death from unexpected circulatory arrest: Engaging the recommendations of the Institute of Medicine." Journal of Law, Medicine, and Ethics, 36, 4 (2008): 731-735.
"Hidden Data for Research Ethics: An Introduction to a Concept and Series of Paper," Journal of Empirical Research on Human Research Ethics, 3,3: (2008): 3-5.
DuBois, J.M., Volpe, R.L., Rangel, E.K., "Hidden empirical research ethics: A review of three health journals from 2005-2006." Journal of Empirical Research on Human Research Ethics, 3,3: (2008): 7-18.
"Is Anesthesia Intrinsically Wrong? On Moral Absolutes and Natural Law Methodology," Christian Bioethics, 14, 2: (2008): 206-216. (Special issue on the thought of G.E.M. Anscombe).
"Avoiding Common Pitfalls in the Determination of Death," National Catholic Bioethics Quarterly, 7, 3, (2007): 545-560.
DuBois, J.M., Dueker, J., Anderson, E., & Campbell, J., "Development and assessment of a NIH-funded research ethics training program," Academic Medicine, 83, 6 (2008): 596-603.
DuBois, J.M. and Smith, B., "Adolf Reinach" in the Stanford Encyclopedia of Philosophy: http://plato.stanford.edu/. Posted September 2008.
DuBois, J.M., Delmonico, F., and D’Alessandro, A. "When Organ Donors Are Still Patients: Is the Pre-mortem Use of Heparin Ethically Acceptable?" American Journal of Critical Care, 16, 4 (2007): 396-400.
DuBois, J.M., and DeVita, M. "Recovering the Truth about Organ Donation Following a Circulatory Determination of Death: A reply to Verheijde, Rady, and McGregor," Critical Care Medicine, 35, 5, (2007): 1440-1441.
DuBois, J.M., and DeVita, M. “Donation after Cardiac Death: How to Move Forward,” Critical Care Medicine, 34, 12 (2007): 3045-47.
(2nd author with E. Anderson) “The need for evidence-based research ethics: A review of the substance abuse literature. Drug and Alcohol Dependence, 86, 2-3 (2006): 95-105.
"How Much Guidance Can a Secular Natural Law Theory Offer," in Mark Cherry (Ed), The Death of Metaphysics, the Death of Culture: Epistemology, Metaphysics, and Morality, (New York, Springer, 2006), pp.
Institute of Medicine, Committee on Increasing Rates of Organ Donation, Organ Donation: Opportunities for Action (Washington, DC: National Academies Press, 2006) [Co-author of report, with James Childress and Catharyn Liverman, Eds]
"Vulnerability in Research," in Robert Amdur and Elizabeth Bankert (Eds), Institutional review Board: Management and Function, 2nd Ed., (Boston: Jones & Bartlett, 2005), 337-340.
(Editor/translator/introduction author). Viktor Frankl. On the Theory and Therapy of Mental Disorders (New York: Brunner-Routledge, 2004). "Understanding Viktor Frankl's Theory and Therapy of Mental Disorders," in V.E. Frankl, On the Theory and Therapy of Mental Disorders (New York: Routledge, 2004), pp. ix - xiii.
"Ethics in Behavioral and Social Science Research," in Ana Iltis (Ed), Research Ethics (Philadelphia: Taylor & Francis, in press).
"Is Compliance a Professional Virtue of Researchers? Reflections on Promoting the Responsible Conduct of Research," Ethics & Behavior, 14, 4 (2004): 383-395.
"Universal Ethical Principles in a Diverse Universe. A Commentary on Monshi and Zieglmayer's Case Study," Ethics & Behavior, 14, 4 (2004): 313-319.
"The Clinician as Moral Facilitator" [review article on John Peteet, Doing the Right Thing: An Approach to Moral Issues in Mental Health. Washington, DC: American Psychiatric Publishing, 2004.] PsychCritiques, 49 (2004): 1.
"Protecting Children vs. Respecting Religious Authority: Lessons Learned from Bioethics," Ethics & Behavior, 14, 1 (2004): 73-77.
"Editor's Introduction: The Varieties of Clinical Consulting Experience," Healthcare Ethics Committee Forum, 15, 4 (2003): 303-309.
"Does the Public Support the Organ Donation Using High-Brain-Death Criteria? A Telephone Survey of 1,000 US Heads of Household," Journal of Clinical Ethics, 14 (2003): 26-35.
"Adolf Reinach's Contributions to Meta-Ethics and the Philosophy of Law," In L. Embree and J. Drummond (Eds), The Phenomenological Tradition in Moral Philosophy, (Dordrecht: Kluwer, 2002): 327-346.
"Does Organ Procurement Cause the Death of Donors?" Issues in Law and Medicine, 18, 1 (2002): 21-41.
"Organ Transplantation: An Ethical Road Map" National Catholic Bioethics Quarterly, 2, 3 (2002): 411-451.
DuBois, J.M., and Ciesla, J.E., "Ethics Education in US Medical Schools: A Study Syllabi," Academic Medicine, 77, 5 (2002): 69-74.
"When Is Informed Consent Appropriate in Educational Research? Ethical and Regulatory Issues," IRB: Ethics & Human Research, 24, 1 (2002): 1-8.
"Non-Heart-Beating Organ Donation: Designing an Ethically Acceptable Protocol," Health Progress, 82 (2001): 18-21.
"Psychotherapy and Ethical Theory: Viktor Frankl's Non-reductive Approach," Logotherapy and Existential Analysis. An Interdisciplinary Journal of Education, Research and Practice, 1 (2000): 39-65.
"Ethical Assessments of Brain Death and Organ Procurement Policies: A Survey of Transplant Personnel in the U.S.," Journal of Transplant Coordination, 9 (1999): 210-217.
"Physician-Assisted Suicide and Public Virtue: A Reply to the Liberty Thesis of the Philosophers' Brief," Issues in Law and Medicine, 15, 2 (1999) 159-179.
"Moral Consciousness in the Light of Biological, Cognitive, and Developmental Research," in T. Slunecko et al. (Eds), Psychologie des Bewusstseins – Bewusstsein der Psychologie (Vienna: University of Vienna Press, 1999), 177-188. (Fitzgerald, RD, DuBois, JM, Shaheen, FA, Schwarz, S, Guttmann, G.)
"Non-Heart-Beating Organ Donation: A Defense of the Required Determination of Death," Journal of Law, Medicine, and Ethics, 27 (1999): 126-136.